Studies on Ascorbic Acid. II

Kinetic Studies on the Reaction of Compound II of Myeloperoxidase with Ascorbic Acid ROLE OF ASCORBIC ACID IN MYELOPEROXIDASE

Ascorbic acid is known to stimulate leukocyte functions. In a recent publication it was suggested that the role of ascorbic acid is to reduce compound II of myeloperoxidase back to the native enzyme (Bolscher, B. G. J. M., Zoutberg, G. R., Cuperus, R. A., and Wever, R. (1984) Biochim. Biophys. Acta 784, 189-191). In this paper we report rapid spectral scan and transient state kinetic results on...

Kinetic studies on the reaction of compound II of myeloperoxidase with ascorbic acid. Role of ascorbic acid in myeloperoxidase function.

Ascorbic acid is known to stimulate leukocyte functions. In a recent publication it was suggested that the role of ascorbic acid is to reduce compound II of myeloperoxidase back to the native enzyme (Bolscher, B. G. J. M., Zoutberg, G. R., Cuperus, R. A., and Wever, R. (1984) Biochim. Biophys. Acta 784, 189-191). In this paper we report rapid spectral scan and transient state kinetic results on...

Studies associated with ascorbic acid.

1) The effect of 1 g daily doses of L-ascorbic acid in reducing the incidence of the common cold in a group of volunteers was compared with a control group receiving a placebo, The survey lasted 16 weeks during the winter months of 1971/1972. The results (1) showed that the 47 volunteers receiving L-ascorbic acid suffered a total of 44 colds, whereas the 43 people taking dummy pills had 80 cold...

Studies of Ascorbic Acid and Rheumatic Fever Ii. Test of Prophylactic and Therapeutic Action of Ascorbic Acid.

Kinetic Studies on the Reaction of Compound II of Myeloperoxidase with Ascorbic Acid

Ascorbic acid is known to stimulate leukocyte functions. In a recent publication it was suggested that the role of ascorbic acid is to reduce compound II of myeloperoxidase back to the native enzyme (Bolscher, B. G. J. M., Zoutberg, G. R., Cuperus, R. A., and Wever, R. (1984) Biochim. Biophys. Acta 784, 189-191). In this paper we report rapid spectral scan and transient state kinetic results on...